Neurology

Within the last few years the CRF has forged very strong links with neurologists both in St James’s hospital and Beaumont hospital. The CRF works on epilepsy studies with Dr Doherty.

We have also conducted Phase I overnight studies with Prof Orla Hardiman, researching treatment in motor neuron disease.

Current Trials & Studies
Study Name Study TitleStudy Type SponsorSponsor Type
BIIB078A Phase I Multiple-Ascending-Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 Administered Intrathecally to Adults with C9ORF72-Associated Amyotrophic Lateral SclerosisClinical TrialBiogenCommercial: Industry
CONCUSSIONAssessment of Concussion in contact sportObservational with radiology or blood testsN/ANon-commercial: Hospital
MotorMarkerimpairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised DiagnosisObservational with radiology or blood testsN/ANon-commercial: Academic
EEG-MMN and EEG-SARTCharacterising Network Disruption in Human Neurodegeneration: A Spectral EEG and TMS based approach in Amyotrophic Lateral SclerosisObservational-non invasiveN/ANon-commercial: Academic
Past Trials & Studies
Study NameStudy TitleStudy TypeSponsorSponsor Type
UCB StudyA Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study To Evaluate The Efficacy And Safety Of Padsevonil As Adjunctive Treatment Of Focal-Onset Seizures In Adult Subjects With Drug-Resistant EpilepsyClinical trialUCBIndustry
EEG in ALS PatientsHigh resolution Spectral EEG recording in Amyotrophic lateral sclerosis; correlation with comprehensive neuropsychological profilingObservational with invasive testsN/AAcademic
EEG and epilepsyThe Acute neroimaging, neurophysiology and clinical data correlation in patients presenting to the emergency Department within 24 hours of seizure onset and at 6 weeks post ictallyObservational with invasive testsN/AAcademic