Hepatology

The Hepatology Department at St James’s hospital, has a long established research program and runs a variety of both clinical trials and investigator led studies.

Current Trials & Studies
Study NameStudy TitleStudy TypeSponsorSponsor Type
NASHA multi-centre, double blind placebo controlled, parallel randomised phase Iia study to investigate the safety, tolerability, pharmacodynamics & pharmacokinetics of different doses of orally administered BI 1467335 during a 12 week period compared to placebo in patients with clinical evidence of NASHClinical TrialBoehringer IngeilheimCommercial: Industry
Abbvie M16-135A Single Arm, Open-label Study to Evaluate the Efficacy and Safety of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment Naïve Adults with Chronic Hepatitis C Virus (HCV) Genotype 1,2, 4, 5 or 6 Infection and Compensated CirrhosisClinical TrialAbbVieCommercial: Industry
NUT-3/NASDouble-blind, randomised, placebo controlled, phase IIb clinical trial on the efficacy and safety of norursodeoxycholic acid tablets in patients with non-alcoholic steatohepatitis (NASH)Clinical TrialDr Falk Pharma GmbHCommercial: Industry
Past Trials & Studies
Study NameStudy TitleStudy TypeSponsorSponsor Type
HCV and Physical ActivityA determination of the relationship between physical activity, cardiovascular risk factors and metabolic profile in adults with Hepatitis CObservational-non invasiveNon-commercial: Academic
Intensive PK StudyDirect Acting Antivirals in Hepatitis C- Developing a personalized model of care: Intensive PK sub-studyObservational with radiology or blood testsNon-commercial: Academic
CANDIViral Hepatitis C Associated Neurocognitive Dysfunction in Ireland in the direct acting antiviral (DAA) era Observational-non invasiveNon-commercial: Academic
NAFLD Exercise InterventionNon-alcoholic Fatty Liver Disease Exercise Intervention ProtocolOtherNon-commercial: Academic