Hepatology

The Hepatology Department at St James’s hospital, has a long established research program and runs a variety of both clinical trials and investigator led studies.

Current Trials & Studies
Study NameStudy TitleStudy TypeSponsorSponsor Type
ESSENCEThe effect of semaglutide in subjects with non-cirrhotic non-alcoholic steatohepatitis Clinical Trial (NCT04822181) (2019-004594-44)Novo Nordisk Commercial: Industry
NUT-3/NASDouble-blind, randomised, placebo controlled, phase IIb clinical trial on the efficacy and safety of norursodeoxycholic acid tablets in patients with non-alcoholic steatohepatitis (NASH)Clinical Trial (2018-003443-31)Dr Falk Pharma GmbHCommercial: Industry
Past Trials & Studies
Study NameStudy TitleStudy TypeSponsorSponsor Type
Abbvie M16-135A Single Arm, Open-label Study to Evaluate the Efficacy and Safety of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment Naïve Adults with Chronic Hepatitis C Virus (HCV) Genotype 1,2, 4, 5 or 6 Infection and Compensated CirrhosisClinical Trial (NCT03089944) (2016-004967-38)AbbVieCommercial: Industry
NASHA multi-centre, double blind placebo controlled, parallel randomised phase Iia study to investigate the safety, tolerability, pharmacodynamics & pharmacokinetics of different doses of orally administered BI 1467335 during a 12 week period compared to placebo in patients with clinical evidence of NASHClinical Trial (NCT03166735) (2016-000499-83)Boehringer IngeilheimCommercial: Industry
HCV and Physical ActivityA determination of the relationship between physical activity, cardiovascular risk factors and metabolic profile in adults with Hepatitis CObservational-non invasiveNon-commercial: Academic
Intensive PK StudyDirect Acting Antivirals in Hepatitis C- Developing a personalized model of care: Intensive PK sub-studyObservational with radiology or blood testsNon-commercial: Academic
CANDIViral Hepatitis C Associated Neurocognitive Dysfunction in Ireland in the direct acting antiviral (DAA) era Observational-non invasiveNon-commercial: Academic
NAFLD Exercise InterventionNon-alcoholic Fatty Liver Disease Exercise Intervention ProtocolOtherNon-commercial: Academic