Cardiology

The Cardiology  Department  at St James’s hospital is actively involved in clinical research. We run both clinical trials and investigator led studies in amyloidosis, dyslipidemia and heart failure.

Current Trials & Studies
Study NameTitle StudyStudy TypeSponsorSponsor Type
AS HRRAn Investigation of Heart Rate Recovery Responses to Repeated Active Stand Protocols Observational Study ( NCT04921059)N/ANon Commercial: Academic
RHEIAA Prospective, Randomized, Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Transcatheter Aortic Valve Implantation as compared to surgery in Female Patients who have Severe Symptomatic Aortic Stenosis Requiring Aortic Valve Replacement Patients Medical Device study (NCT04160130) SS International Clinical Research Commercial : Industry
CroiValve A Study of the Feasibility, Safety and Performance of Temporary Implantation of the CroíValve Coaptation Valve for Evaluation of Correction of Severe Tricuspid Incompetence in Human Patients Medical Device StudyCroiValveCommercial: Industry
ETNANon-interventional Study on Edoxaban Treatment in Routine Clinical Practice for Patients with Non-Valvular Atrial Fibrillation Observational Study (NCT02944019) Daiichi Sankyo, Inc Commercial Industry
HELIOSA Study to Evaluate Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy Find out more: https://clinicaltrials.gov/ct2/show/NCT04153149?term=helios&cntry=IE&draw=2&rank=2 Clinical Trial AlnylamIndustry
SANTORINITreatment of High and Very high riSk dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events in Europe – a MultInatioNal ObservatIonal Study (SANTORINI)Non-Interventional studyDaiichi Sankyo Europe GmbHAcademic
Past Trials & Studies
Study NameStudy TitleStudy TypeSponsorSponsor Type
EDifyEffect of ivabradine versus placebo on cardiac function, exercise capacity and neuroendocrine activation in patients with Chronic Heart Failure with Preserved left ventricular Ejection Fraction. Find out more: https://clinicaltrials.gov/ct2/show/NCT00757055?term=ivabradine&cntry=IE&draw=2&rank=1Clinical trialServierIndustry
ASPIREIreland-Aspire Survey of Cardiovascular Disease Prevention and DiabetesNon-interventionalAcademic
IHF ASA IHF Aspirin Study (DCCR) Observational with radiology or blood tests Charity Irish Heart Foundation Charity
ARIADNEAssessment of Real Life Care - Describing European Heart Failure Management (ARIADNE)Non-interventionalNovartisIndustry
Lab study novel biomarkers Novel Markers of Plaque Rupture and Platelet Activation in Patients with Chest Pain Observational with radiology or blood tests Health Research Board Non-commercial: Academic